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Blood sampling can be stressful for laboratory animals because of the handling, restraint, anaesthesia or discomfort associated with a particular technique

The suffering that animals experience when they are used in research and testing is a very serious concern. We believe that every possible step must be taken to reduce animal suffering to an absolute minimum.

The IMPROVE Guidelines (Ischaemia Models: Procedural Refinements Of in Vivo Experiments) - have been published in the Journal of Cerebral Blood Flow and Metabolism

Good training in non-aversive handling has benefits for the animal, for the handler and for the reliability of data gained in experiments.

In 2008, the UFAW/RSPCA Rabbit Behaviour and Welfare Group produced a resource that sets out practical guidance on fulfilling the basic needs of the rabbit.

Collecting blood for serology testing from research animals can be a challenging process that leads to increased stress in your animal. Exclusive to Charles River, our HemaTIP™ microsampler simplifies this process by placing the collection media on the tip of an easy-to-hold stylus.

There are several stages to consider when planning and carrying out studies involving animals to establish, implement and refine humane endpoints.

A resource from the research animals department on how housing and care can be refined to reduce suffering and improve welfare of animal species.

Animal Welfare  is an international scientific and technical journal. It publishes the results of peer-reviewed scientific research, technical studies and reviews relating to the welfare of kept animals (eg on farms, in laboratories, zoos and as companions) and of those in the wild whose welfare is compromised by human activities.

Official Journal of the International Society for Applied Ethology (ISAE) An international journal reporting on the application of ethology to animals managed by humans.

Laboratory Animals is an international journal of laboratory animal science and welfare. Laboratory Animals publishes peer-reviewed original papers and reviews on all aspects of the use of animals in biomedical research. The journal promotes improvements in the welfare or well-being of the animals used, it particularly focuses on research that reduces the number of animals used or which replaces animal models with in vitro alternatives.

Laboratory Animals publishes papers dealing with all aspects of the use of animals in biomedical research, including: new animal models; laboratory animal microbiology; clinical case reports; descriptions of new or improved research techniques; reports on the influence of environmental and other variables on research results; descriptions of techniques which offer replacements for in vivo models; and basic data characterizing the haematology, biochemistry or pathology of new or existing animal models. Papers describing work which involves a reduction in the number of animals that need to be used; or which replace animals with in vitro alternatives; or which represent a significant refinement in methodology, leading to improvements in the welfare or wellbeing of the animals used, are especially encouraged.