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The Foundation for Liver Research UK was established in 1974 to develop and extend research into diseases of the human liver and to enhance medical research generally.

CLDF supports a wide range of projects, including clinical and laboratory-based research, lately moving into social research which looks at topics such as how to improve quality of life. 

Recommendations for Excellence: as part of ongoing efforts to reduce waste and increase the reproducibility of animal research and testing, a group of experts led by the Secretary of Norecopa has produced a set of guidelines for planning animal experiments

The International Society for Pharmacoepidemiology (ISPE) is a non-profit international professional membership organization dedicated to advancing the health of the public by providing a forum for the open exchange of scientific information and for the development of policy; education; and advocacy for the field of pharmacoepidemiology, including pharmacovigilance, drug utilization research, outcomes research, comparative effectiveness research, and therapeutic risk management.

Laboratory Animals is an international journal of laboratory animal science and welfare. Laboratory Animals publishes peer-reviewed original papers and reviews on all aspects of the use of animals in biomedical research. The journal promotes improvements in the welfare or well-being of the animals used, it particularly focuses on research that reduces the number of animals used or which replaces animal models with in vitro alternatives.

Laboratory Animals publishes papers dealing with all aspects of the use of animals in biomedical research, including: new animal models; laboratory animal microbiology; clinical case reports; descriptions of new or improved research techniques; reports on the influence of environmental and other variables on research results; descriptions of techniques which offer replacements for in vivo models; and basic data characterizing the haematology, biochemistry or pathology of new or existing animal models. Papers describing work which involves a reduction in the number of animals that need to be used; or which replace animals with in vitro alternatives; or which represent a significant refinement in methodology, leading to improvements in the welfare or wellbeing of the animals used, are especially encouraged.

The Swiss 3R Competence Centre (3RCC) promotes the 3Rs principle (replacement, reduction and refinement of animal experimentation) among the scientific community and the public. To facilitate the development and implementation of effective 3R methods and improve animal welfare it challenges research paradigms and creates innovative alternatives to animal use.

CELPHEDIA (Creation, Breeding, Phenotyping, Distribution and Archiving of model organisms) is a national operational research infrastructure distributed over the French territory. Its mission is to support academic and industrial scientific community to accelerate discoveries in biology and improve biomedical research.