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The International Society for Pharmacoepidemiology (ISPE) is a non-profit international professional membership organization dedicated to advancing the health of the public by providing a forum for the open exchange of scientific information and for the development of policy; education; and advocacy for the field of pharmacoepidemiology, including pharmacovigilance, drug utilization research, outcomes research, comparative effectiveness research, and therapeutic risk management.

The Swiss 3R Competence Centre (3RCC) promotes the 3Rs principle (replacement, reduction and refinement of animal experimentation) among the scientific community and the public. To facilitate the development and implementation of effective 3R methods and improve animal welfare it challenges research paradigms and creates innovative alternatives to animal use.

CELPHEDIA (Creation, Breeding, Phenotyping, Distribution and Archiving of model organisms) is a national operational research infrastructure distributed over the French territory. Its mission is to support academic and industrial scientific community to accelerate discoveries in biology and improve biomedical research.

ATLA is published by  FRAME, and has been a key scientific journal in the field of laboratory animal alternatives for more than 30 years. Circulated worldwide, ATLA is distributed to individuals, organisations and institutions. It covers the  latest research relating to alternatives to the use of laboratory animals.

AALAS is an association of professionals that advances responsible laboratory animal care and use to benefit people and animals.

Toxicology Data Network- is a group of databases covering chemicals and drugs, diseases and the environment, environmental health, occupational safety and health, poisoning, risk assessment and regulations, and toxicology.

Vaccination of animals against disease protects them from suffering. However, this comes with an animal welfare cost - the safety and efficacy of vaccines is assessed in experimental animals and the tests involved can cause significant pain and distress. There is an ethical dilemma in protecting one set of animals at the expense of others but implementation of the 3Rs can help to resolve this. The research animals department works with researchers involved in vaccine testing and regulators to promote the 3Rs in this important area.

ALTEX publishes original articles, short communications, and reviews, as well as news and comments, meeting reports, and book reviews. Animal experiments are defined by the editors as all experimental procedures involving the use of animals in testing, research, and education, or to obtain tissues, organs, and other animal derived products that may cause pain or distress to animals..

Initiate activities that may lead to the immediate implementation of the 3Rs.