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3Rs

Systematic Review Facility

SyRF is a fully integrated online platform for performing systematic reviews of preclinical studies.

Topic: Reduction

The Design of Animal Experiments

"The Design of Animal Experiments" is intended for all research scientists who use laboratory animals, with the aim of helping them to design their own experiments more effectively.

Topic: Reduction

Isogenic Strains

Isogenic strains (inbred strains and F1 hybrids) are like immortal clones of genetically identical individuals. The same genotype can be reproduced indefinitely. They have already made a substantial contribution to biomedical research. 

Topic: Reduction

Reducing Mouse Numbers by Measuring Tumour Size Non-Invasively

Scientists at the ICR are increasingly using non-invasive methods to measure the size of tumours in mice – allowing the same mouse to be assessed several times and reducing the overall numbers

Topic: Reduction

SABRE Research UK

Systematic reviews: Evidence from animal research is considered by researchers to be of the lowest quality in medical research.

Topic: Reduction

Discipline tool

Human Bone Models Invitro
Topic: Bone

Bone Cancer Research Trust
Topic: Bone

Drug Discovery Today: Disease Models Bone Biology in Animal models, Including Testing of Bone Biomaterials.
Topic: Bone

General Database Information

Pharmacoepidemiology

The International Society for Pharmacoepidemiology (ISPE) is a non-profit international professional membership organization dedicated to advancing the health of the public by providing a forum for the open exchange of scientific information and for the development of policy; education; and advocacy for the field of pharmacoepidemiology, including pharmacovigilance, drug utilization research, outcomes research, comparative effectiveness research, and therapeutic risk management.

Topic: Information on drugs and diseases

Nuffield Bioethics

The issues addressed in this Report have been a subject of intense public debate over at least the past four hundred years. Feelings are strong on all sides of the issues, and in recent years reports of violent action against those conducting animal research in the UK have brought the matter to the forefront of public attention.

Topic: Ethics

Swiss 3R Competence Centre

The Swiss 3R Competence Centre (3RCC) promotes the 3Rs principle (replacement, reduction and refinement of animal experimentation) among the scientific community and the public. To facilitate the development and implementation of effective 3R methods and improve animal welfare it challenges research paradigms and creates innovative alternatives to animal use.

Topic: "Three Rs"

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