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The mission statement of the 3Rs-Centre Utrecht Life Sciences (ULS) is to stimulate the development, acceptance and implementation of methods which can Replace, Reduce and Refine (the 3Rs) animal experiments. The centre is affiliated with Utrecht Life Sciences and provides information and advice to the Animal Welfare Body of both Utrecht University and the University Medical Centre Utrecht.

A mainly government funded body which provides input to the UK’s Three Rs agenda, carries out research and provides funds for Three R research. 

The Biosciences Federation Animal Science Group was established in December 2002 and launched in September 2003 as an umbrella organisation to promote interaction within the biosciences community, particularly in areas of research and teaching; to provide information to assist the formulation of scientific policy; and, perhaps most challenging of all, to debate the ethical issues surrounding recent advances in the biosciences (see previous report by Nancy Rothwell).

The EURL ECVAM DataBase service on ALternative Methods (DB-ALM).

TSAR is a tool aimed at providing a transparent view on the status of alternative methods as they progress from purely scientific protocols submitted for eventual validation to being actively used in a regulatory context. This tracking system intends to cover all steps, from the initial submission for validation until final adoption by inclusion in the EU legislation and/or related Guidance Documents, when appropriate.   

AMC Tool is a programme to calculate antimicrobial consumption. It is aimed to replace the old ABC Calc tool.

Recommendations for Excellence: as part of ongoing efforts to reduce waste and increase the reproducibility of animal research and testing, a group of experts led by the Secretary of Norecopa has produced a set of guidelines for planning animal experiments