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IMPROVE-ing Animal Welfare in Experimental Stroke Research

Over the last two years, representatives from the UK’s stroke research community have been working, in a collaboration led by the NC3Rs, to improve the welfare and increase the scientific value of rodent models of stroke. The findings from the collaboration - The IMPROVE Guidelines (Ischaemia Models: Procedural Refinements Of in Vivo Experiments)  have been published in the Journal of Cerebral Bloodflow and Metabolism.

Topic: Cardiology

Liverpool University Vetschool Cardiology Department
Topic: Cardiology

Penn Vet School Cardiology Research
Topic: Cardiology

Journal of Veterinary Cardiology
Topic: Cardiology

Animal Research in Pediatric Cardiology and Cardiac Surgery Paper and Pediatric Journal
Topic: Cardiology

JACC: Cardiovascular Interventions Open Access Journal
Topic: Cardiology

General Database Information

Dutch 3Rs Centre- Utrecht Life Sciences
Topic: "Three Rs"

Consensus Meetings on the Care and Use of Fish Wildlife and Agricultural Animals in Research

Consensus meetings on the care and use of fish, wildlife and agricultural animals in research is provided by Norecopa. It contains presentations, guidelines and consensus statements from four international meetings covering all Three Rs, is in English and free of charge.

Topic: Other Resources

US Food and Drug Administration (USFDA)
Topic: Information on drugs and diseases

The Nordic Pharmaco Epidemiological Network (NorPEN)

NorPEN is a network of researchers with the purpose of facilitating research within the field of pharmacoepidemiology in the Nordic countries. The website

Topic: Information on drugs and diseases

European Consensus Platform for Alternatives (ECOPA)
Topic: "Three Rs"

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