Over the last two years, representatives from the UK’s stroke research community have been working, in a collaboration led by the NC3Rs, to improve the welfare and increase the scientific value of rodent models of stroke. The findings from the collaboration - The IMPROVE Guidelines (Ischaemia Models: Procedural Refinements Of in Vivo Experiments) have been published in the Journal of Cerebral Bloodflow and Metabolism.
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IMPROVE-ing Animal Welfare in Experimental Stroke Research
Topic: Cardiology
Jax Phenotype-Cardiovascular
Topic: Cardiology
Liverpool University Vetschool Cardiology Department
Topic: Cardiology
Penn Vet School Cardiology Research
Topic: Cardiology
Journal of Veterinary Cardiology
Topic: Cardiology
Animal Research in Pediatric Cardiology and Cardiac Surgery Paper and Pediatric Journal
Topic: Cardiology
JACC: Cardiovascular Interventions Open Access Journal
Topic: Cardiology
General Database Information
PREPARE (Planning Research and Experimental Procedures on Animals)
Recommendations for Excellence: as part of ongoing efforts to reduce waste and increase the reproducibility of animal research and testing, a group of experts led by the Secretary of Norecopa has produced a set of guidelines for planning animal experiments
Topic: "Three Rs"
CAAT-Europe (Centre of Alternatives to Animal Testing)
Topic: Alternative methods, Information on drugs and diseases
The Royal Society for the Prevention of Cruelty to Animals (RSPCA)
Topic: "Three Rs"
Pharmacoepidemiology
The International Society for Pharmacoepidemiology (ISPE) is a non-profit international professional membership organization dedicated to advancing the health of the public by providing a forum for the open exchange of scientific information and for the development of policy; education; and advocacy for the field of pharmacoepidemiology, including pharmacovigilance, drug utilization research, outcomes research, comparative effectiveness research, and therapeutic risk management.
Topic: Information on drugs and diseases
Swiss 3R Competence Centre
The Swiss 3R Competence Centre (3RCC) promotes the 3Rs principle (replacement, reduction and refinement of animal experimentation) among the scientific community and the public. To facilitate the development and implementation of effective 3R methods and improve animal welfare it challenges research paradigms and creates innovative alternatives to animal use.
Topic: "Three Rs"