The Foundation for Liver Research UK was established in 1974 to develop and extend research into diseases of the human liver and to enhance medical research generally.
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CLDF supports a wide range of projects, including clinical and laboratory-based research, lately moving into social research which looks at topics such as how to improve quality of life.
General Database Information
The EURL ECVAM DataBase service on ALternative Methods (DB-ALM).
The International Society for Pharmacoepidemiology (ISPE) is a non-profit international professional membership organization dedicated to advancing the health of the public by providing a forum for the open exchange of scientific information and for the development of policy; education; and advocacy for the field of pharmacoepidemiology, including pharmacovigilance, drug utilization research, outcomes research, comparative effectiveness research, and therapeutic risk management.
Guiding principles on good practice for Animal Welfare and Ethical Review Bodies (2015) (PDF 1.76MB). Developed and published jointly by the RSPCA and the Laboratory Animal Science Association (LASA), this resource aims to help in the efficient and effective operation of local animal welfare and ethical review bodies.
The CAMARADES collaboration provides a supporting framework for groups involved in the systematic review and meta-analysis of data from experimental animal studies.
Our interests range from identifying potential sources of bias in animal work; developing recommendations for improvements in the design and reporting of animal studies; developing the meta-analysis methodology the better to apply it to animal studies; through to the selection of candidate stroke drugs for clinical trial.
CAMARADES aims to provide a central focus for data sharing; to act as a resource for those wishing to carry out such reviews; to provide a web based stratified meta-analysis bioinformatics engine (under development!); and to act as a repository for completed reviews.
Modern human-relevant technology has the potential to provide answers traditionally sought through animal research. Yet in many of these areas there is little momentum to transition away from animal use. Education is a key driver that helps increase the impetus for change.
Replacing Animal Research believes that a whole system approach to replacing animals in research is the best way to facilitate change and ensure the development and uptake of human-relevant research methods. This system is driven by the work and choices made by various stakeholders including funders, journal editors, regulators, industry, academics, legislators, and of course scientists. Relevant training and awareness of the current research landscape are important in these roles to help inform valid scientific and ethical choices, and help prioritise non-animal research.. Through education it is possible to share information about the system, develop confidence in the use of alternative methods, and challenge the use of animals in different areas of research and testing.