"The Design of Animal Experiments" is intended for all research scientists who use laboratory animals, with the aim of helping them to design their own experiments more effectively.
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3Rs
Isogenic strains (inbred strains and F1 hybrids) are like immortal clones of genetically identical individuals. The same genotype can be reproduced indefinitely. They have already made a substantial contribution to biomedical research.
Scientists at the ICR are increasingly using non-invasive methods to measure the size of tumours in mice – allowing the same mouse to be assessed several times and reducing the overall numbers
Systematic reviews: Evidence from animal research is considered by researchers to be of the lowest quality in medical research.
There is a great need for valuable ex vivo models that allow for assessment of cartilage repair strategies to reduce the high number of animal experiments.
General Database Information
CELPHEDIA (Creation, Breeding, Phenotyping, Distribution and Archiving of model organisms) is a national operational research infrastructure distributed over the French territory. Its mission is to support academic and industrial scientific community to accelerate discoveries in biology and improve biomedical research.
Toxicology Data Network- is a group of databases covering chemicals and drugs, diseases and the environment, environmental health, occupational safety and health, poisoning, risk assessment and regulations, and toxicology.
Embase is a crucial resource for discovering biomedical evidence within published, peer-reviewed literature, in-press publications and conference abstracts.
Researchers can apply for access to data from health registries and health studies, as well as biological material from the biobanks. Here you will find guidelines and electronic application forms.