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University Biomedical Services (UBS)

 

General Database Information

The Nordic Pharmaco Epidemiological Network (NorPEN)
Topic: Information on drugs and diseases

Procedures With Care

Procedures with Care Website by Newcastle University, NC3Rs and IAT, provides a series of resources to support the adoption of best practice for commonly used procedures in animal research. The focus is on rats and mice but further material will be added to expand the range of techniques and species in the future.   

Topic: Other Resources

Animal Research Info

Animal Research Info-is an international collaboration of scientists and researchers. As expert contributors, we provide and edit the content, making it as accurate and up-to-date as possible.

Topic: Information on drugs and diseases

WHO Collaborating Centre for International Drug Monitoring (UMC)

UMC regularly publishes scientific papers in a range of international journals. These papers record progress and results from research into clinical or methodological issues in pharmacovigilance.

Topic: Information on drugs and diseases

Searching for 3Rs Information- Published Literature Sources

There is a legal and ethical obligation to reduce the numbers of animals in research and to enhance the welfare of those that are used. This has led to an increased need for access to information on this topic. To help meet these obligations, members of the UK Pharmaceutical Industry set up a working party of information experts (I3R) with the aim "to encourage the development of best practice in the provision and retrieval of information on alternatives to animals in pharmaceutical R&D with special reference to Refinement, Reduction and Replacement (3Rs)." 

Topic: Other Resources

European Medicines Agency (EMA-EUROPA)

The European Medicines Agency (EMA) is a decentralised agency of the European Union (EU), located in London. It began operating in 1995. The Agency is responsible for the scientific evaluation, supervision and safety monitoring of medicines developed by pharmaceutical companies for use in the EU.

Topic: Information on drugs and diseases

The Medical Research Council

The MRC ethics series document ‘Good research practice: principles and guidelines’ sets out the MRC’s expectations for MRC research units and institutes, MRC university units, MRC centres and MRC grant holders in the form of principles, guidelines and standards to foster good research practice in all MRC-funded research.

Topic: Information on drugs and diseases

ARRIVE Guidelines

ARRIVE (Animal Research: Reporting of In Vivo Experiments) guidelines are intended to improve the reporting of research using animals – maximising information published and minimising unnecessary studies.

Topic: Other Resources

Medicines Evaluations Board

The Medicines Evaluation Board assesses and monitors the efficacy, risks and quality of human and veterinary medicines, and the safety of novel foods for human consumption.

Topic: Information on drugs and diseases

The Interspecies Database

The Interspecies Database helps researchers to make an optimal choice of species and strain of the animal model, which is essential for efficient extrapolation of animal data to humans or other animals. Thee database has initially been developed by the National Institute for Public Health and the Environment (RIVM) and the Dutch Ministry of Health, Welfare and Sports. It is offered by the 3Rs-Centre ULS in collaboration with the RIVM.

Topic: Information on drugs and diseases

WHO Collaborating Centre for Drug Statistics Methodology
Topic: Information on drugs and diseases

CAMARADES

The CAMARADES collaboration provides a supporting framework for groups involved in the systematic review and meta-analysis of data from experimental animal studies. 

Our interests range from identifying potential sources of bias in animal work; developing recommendations for improvements in the design and reporting of animal studies; developing the meta-analysis methodology the better to apply it to animal studies; through to the selection of candidate stroke drugs for clinical trial. 

CAMARADES aims to provide a central focus for data sharing; to act as a resource for those wishing to carry out such reviews; to provide a web based stratified meta-analysis bioinformatics engine (under development!); and to act as a repository for completed reviews.

Topic: Other Resources

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