Over the last two years, representatives from the UK’s stroke research community have been working, in a collaboration led by the NC3Rs, to improve the welfare and increase the scientific value of rodent models of stroke. The findings from the collaboration - The IMPROVE Guidelines (Ischaemia Models: Procedural Refinements Of in Vivo Experiments) have been published in the Journal of Cerebral Bloodflow and Metabolism.
- (-) Remove Information on drugs and diseases filter Information on drugs and diseases
- (-) Remove Cardiology filter Cardiology
- (-) Remove Guinea Pig filter Guinea Pig
- (-) Remove Hamster filter Hamster
- (-) Remove Dog filter Dog
- (-) Remove Portals and Websites filter Portals and Websites
Discipline tool
General Database Information
The European Medicines Agency (EMA) is a decentralised agency of the European Union (EU), located in London. It began operating in 1995. The Agency is responsible for the scientific evaluation, supervision and safety monitoring of medicines developed by pharmaceutical companies for use in the EU.
A mainly government funded body which provides input to the UK’s Three Rs agenda, carries out research and provides funds for Three R research.
The MRC ethics series document ‘Good research practice: principles and guidelines’ sets out the MRC’s expectations for MRC research units and institutes, MRC university units, MRC centres and MRC grant holders in the form of principles, guidelines and standards to foster good research practice in all MRC-funded research.
The Medicines Evaluation Board assesses and monitors the efficacy, risks and quality of human and veterinary medicines, and the safety of novel foods for human consumption.
TSAR is a tool aimed at providing a transparent view on the status of alternative methods as they progress from purely scientific protocols submitted for eventual validation to being actively used in a regulatory context. This tracking system intends to cover all steps, from the initial submission for validation until final adoption by inclusion in the EU legislation and/or related Guidance Documents, when appropriate.