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NC3Rs-New Device for Refined Neural Recording in Mice Could Transform Dementia Research

Research published in Scientific Reports describes a new ultra lightweight system for recording neural activity in the brains of mice.

Topic: Aged

MouseAGE

MouseAGE is opening a call for European researchers to establish their infrastructure needs in the area of ageing and age-related disorders at the preclinical stage with a view to coordinate efforts for applications for funding.

Topic: Aged

General Database Information

European Medicines Agency (EMA-EUROPA)

The European Medicines Agency (EMA) is a decentralised agency of the European Union (EU), located in London. It began operating in 1995. The Agency is responsible for the scientific evaluation, supervision and safety monitoring of medicines developed by pharmaceutical companies for use in the EU.

Topic: Information on drugs and diseases

ARRIVE Guidelines

ARRIVE (Animal Research: Reporting of In Vivo Experiments) guidelines are intended to improve the reporting of research using animals – maximising information published and minimising unnecessary studies.

Topic: Other Resources

The Medical Research Council

The MRC ethics series document ‘Good research practice: principles and guidelines’ sets out the MRC’s expectations for MRC research units and institutes, MRC university units, MRC centres and MRC grant holders in the form of principles, guidelines and standards to foster good research practice in all MRC-funded research.

Topic: Information on drugs and diseases

Medicines Evaluations Board

The Medicines Evaluation Board assesses and monitors the efficacy, risks and quality of human and veterinary medicines, and the safety of novel foods for human consumption.

Topic: Information on drugs and diseases

The Interspecies Database

The Interspecies Database helps researchers to make an optimal choice of species and strain of the animal model, which is essential for efficient extrapolation of animal data to humans or other animals. Thee database has initially been developed by the National Institute for Public Health and the Environment (RIVM) and the Dutch Ministry of Health, Welfare and Sports. It is offered by the 3Rs-Centre ULS in collaboration with the RIVM.

Topic: Information on drugs and diseases

WHO Collaborating Centre for Drug Statistics Methodology
Topic: Information on drugs and diseases

CAMARADES

The CAMARADES collaboration provides a supporting framework for groups involved in the systematic review and meta-analysis of data from experimental animal studies. 

Our interests range from identifying potential sources of bias in animal work; developing recommendations for improvements in the design and reporting of animal studies; developing the meta-analysis methodology the better to apply it to animal studies; through to the selection of candidate stroke drugs for clinical trial. 

CAMARADES aims to provide a central focus for data sharing; to act as a resource for those wishing to carry out such reviews; to provide a web based stratified meta-analysis bioinformatics engine (under development!); and to act as a repository for completed reviews.

Topic: Other Resources

World Health Organisation-Latest News
Topic: Information on drugs and diseases

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