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The use of animals in research, teaching and testing is an important ethical and political issue. Much of the discussion about this issue revolves around the relative value, often referred to as 'moral value', of humans and animals.

Over the past twenty years or so, there has been a ‘revolution’ in the life sciences,and our knowledge and capabilities have dramatically increased. At the same time, these advances have raised very important ethical concerns in both the scientific community and with the public at large.

A special report can be found on this page titled: Utility and Morality:Contemporary Tradeoffs. Within this report there is an article by Bernard E. Rollin titled The Moral Status of Invasive Animal Research.

The Xenopus Model Welfare Organization will make the use of xenopus as a model organism better by promoting model specific, species specific knowledge and making that knowledge readily available to all stakeholders, including researchers, animal care supervisors, veterinarians, IACUC’s, and government oversight entities. It will influence the care, well-being, and welfare of xenopus as a model for years to come. It will be a compassionate entity that supports the care of xenopus frogs in research institutions and supports the people using xenopus by promoting science based, practical knowledge that can be used by all.

Xenbase's mission is to provide the international research community with a comprehensive, integrated and easy to use web based resource that gives access the diverse and rich genomic, expression and functional data available from Xenopus research. Xenbase also provides a critical data sharing infrastructure for many other NIH-funded projects, and is a focal point for the Xenopus community. In addition to our primary goal of supporting Xenopus researchers, Xenbase enhances the availability and visibility of Xenopus data to the broader biomedical research community.