Isogenic strains (inbred strains and F1 hybrids) are like immortal clones of genetically identical individuals. The same genotype can be reproduced indefinitely. They have already made a substantial contribution to biomedical research.
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3Rs
Scientists at the ICR are increasingly using non-invasive methods to measure the size of tumours in mice – allowing the same mouse to be assessed several times and reducing the overall numbers
Systematic reviews: Evidence from animal research is considered by researchers to be of the lowest quality in medical research.
There is a great need for valuable ex vivo models that allow for assessment of cartilage repair strategies to reduce the high number of animal experiments.
General Database Information
Procedures with Care Website by Newcastle University, NC3Rs and IAT, provides a series of resources to support the adoption of best practice for commonly used procedures in animal research. The focus is on rats and mice but further material will be added to expand the range of techniques and species in the future.
Guiding principles on good practice for Animal Welfare and Ethical Review Bodies (2015) (PDF 1.76MB). Developed and published jointly by the RSPCA and the Laboratory Animal Science Association (LASA), this resource aims to help in the efficient and effective operation of local animal welfare and ethical review bodies.
ARRIVE (Animal Research: Reporting of In Vivo Experiments) guidelines are intended to improve the reporting of research using animals – maximising information published and minimising unnecessary studies.
The University of Minnesota community strives to meet the highest ethical standards in the planning and conduct of research.
The Cambridge Centre for Animal Rights Law is an academic centre of competence dedicated to the study of fundamental rights for non-human animals and is based in Cambridge, UK. The Centre builds on the success of the Talking Animals, Law & Philosophy series which has become a renowned forum for exchange of research in animal rights law ever since its inception in 2015.
Cambridge Human Biology Research Ethics Committee considers applications for ethical approval for research programmes in human biology.