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IMPROVE-ing Animal Welfare in Experimental Stroke Research

Over the last two years, representatives from the UK’s stroke research community have been working, in a collaboration led by the NC3Rs, to improve the welfare and increase the scientific value of rodent models of stroke. The findings from the collaboration - The IMPROVE Guidelines (Ischaemia Models: Procedural Refinements Of in Vivo Experiments)  have been published in the Journal of Cerebral Bloodflow and Metabolism.

Topic: Cardiology

Liverpool University Vetschool Cardiology Department
Topic: Cardiology

Penn Vet School Cardiology Research
Topic: Cardiology

Journal of Veterinary Cardiology
Topic: Cardiology

Animal Research in Pediatric Cardiology and Cardiac Surgery Paper and Pediatric Journal
Topic: Cardiology

JACC: Cardiovascular Interventions Open Access Journal
Topic: Cardiology

General Database Information

Understanding Animal Research

Understanding Animal Research aim to provide all you want to know about animal research, whether you are a concerned member of the public or have a special interest.

Topic: Ethics

Research Animal resources (US)

The use of animals in research, teaching and testing is an important ethical and political issue. Much of the discussion about this issue revolves around the relative value, often referred to as 'moral value', of humans and animals.

Topic: Ethics

NC3Rs: National Centre for Three Rs, UK

A mainly government funded body which provides input to the UK’s Three Rs agenda, carries out research and provides funds for Three R research. 

Topic: Portals and Websites

The Macaque Website

The Macaque Website is a free resource for everyone who works with, or is interested in, laboratory macaques: animal care staff and technicians, facility managers, veterinarians, researchers, students, policy makers and IACUC/AWERB members. Developed by the UK’s National Centre for the Replacement, Refinement and Reduction of Animals in Research (NC3Rs), this site provides referenced information and practical guidance on the natural history and behaviour of macaques, their care and management in captivity, and ways to assess their welfare.

Topic: Other Resources

European Science Foundation Policy on Animal Use 2001

Over the past twenty years or so, there has been a ‘revolution’ in the life sciences,and our knowledge and capabilities have dramatically increased. At the same time, these advances have raised very important ethical concerns in both the scientific community and with the public at large.

Topic: Ethics

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