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FRAME is dedicated to the development of new and valid methods that will replace the need for laboratory animals in medical and scientific research, education, and testing. Where the use of animals is currently necessary, FRAME supports the reduction of numbers involved to an unavoidable minimum and refinement of experimental procedures to minimise any suffering caused. The E-learning resource of FRAME has been set up to provide teachers, school children, students and general supporters with information about the different areas of animal experimentation and with specific resources as to how it can be reduced, refined or replaced. 

The use of animals in scientific research remains a vital tool in improving our understanding of how biological systems work both in health and disease, and in the development of new medicines, treatments and technologies. Underpinning this research is a strong commitment to maintaining a rigorous regulatory system which ensures that animal research is carried out only where no practicable alternative exists and under controls which keep suffering to a minimum. This is achieved through robustly applying the principles of the 3Rs to all research proposals involving the use of animals.

The website is maintained by Norecopa. It covers all Three Rs, is in English and free of charge.  

Guidlines from the British Psychological Society's Standing Advisory Committee on the Welfare of Animals in Psychology. This was developed in cooperation with EPS.

Humane Endpoints Website is provided by 3Rs-Centre Utrecht Life Sciences, gives insight into the recognition and application of humane endpoints in rodents. The website contributes to refinement, the prevention of unnecessary suffering in laboratory animals, by offering information, videos and photographs of rodent species. In addition, the website provides free training modules (accessible after registration). The site is currently available in EN, NL and FR. DE and ES will follow soon.

Understanding Animal Research aim to provide all you want to know about animal research, whether you are a concerned member of the public or have a special interest.

The website is maintained by Norecopa. It covers all Three Rs, is in English and free of charge.  

The use of animals in research, teaching and testing is an important ethical and political issue. Much of the discussion about this issue revolves around the relative value, often referred to as 'moral value', of humans and animals.