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Over the last two years, representatives from the UK’s stroke research community have been working, in a collaboration led by the NC3Rs, to improve the welfare and increase the scientific value of rodent models of stroke. The findings from the collaboration - The IMPROVE Guidelines (Ischaemia Models: Procedural Refinements Of in Vivo Experiments) have been published in the Journal of Cerebral Bloodflow and Metabolism.
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Welcome to this NC3Rs wiki on refinement of the use of chronic implants in neuroscience research using NHPs.
Here you can read, post and edit practical information on the design, implantation and maintenance of headposts, recording chambers and other implants. The wiki also includes information on non-invasive approaches to head restraint.