3Rs - search page

Over the last two years, representatives from the UK’s stroke research community have been working, in a collaboration led by the NC3Rs, to improve the welfare and increase the scientific value of rodent models of stroke. The findings from the collaboration - The IMPROVE Guidelines (Ischaemia Models: Procedural Refinements Of in Vivo Experiments)  have been published in the Journal of Cerebral Bloodflow and Metabolism.

This page provides access to searchable, hypertext listings of inbred strains of mice and inbred strains of rats. Both sets of information were provided by Dr. Michael FW Festing (MRC Toxicology Unit) and were converted for Web presentation by the Mouse Genome Informatics Group at The Jackson Laboratory.

The Sanger Mouse Genetics Programme (Sanger MGP) was initiated in 2006 to advance the functional understanding of protein coding and non-coding RNA genes using a standardised high-throughput phenotypic screen designed to contribute to improved diagnosis and treatment of human disease.

INFRAFRONTIER aims to build a world-class research infrastructure that provides the biomedical research community with the tools needed to unravel the role of gene function in human disease.

General information collated to help with the implementation of approaches to reduce and refine the use of GA mice.