3Rs - search page

The Canadian Centre for Alternatives to Animal Methods (CCAAM) and the Canadian Centre for the Validation of Alternative Methods (CaCVAM) aim to develop, validate, and promote non-animal, human biology-based platforms in biomedical research, education, and chemical safety testing.

Understanding Animal Research aim to provide all you want to know about animal research, whether you are a concerned member of the public or have a special interest.

The use of animals in research, teaching and testing is an important ethical and political issue. Much of the discussion about this issue revolves around the relative value, often referred to as 'moral value', of humans and animals.

ALTBIB is a search tool that retrieves PubMed citations on alternatives to the use of live vertebrates in biomedical research and testing. It includes citations from published articles, books, book chapters, and technical reports. It also provides links to news sources and additional resources on alternatives to animal testing.

A wide variety of topics are covered, including biologics and vaccines, carcinogenesis, cytotoxicity, ecotoxicity, genotoxicity, hepatic/renal toxicity, immunotoxicity/immunology, neurotoxicity, ocular toxicity, pharmacokinetic/mechanistic studies, pyrogenicity, pulmonary toxicity, quantitative structure activity relationship (QSAR), reproductive and developmental toxicity, skin toxicity, and animal welfare.

Over the past twenty years or so, there has been a ‘revolution’ in the life sciences,and our knowledge and capabilities have dramatically increased. At the same time, these advances have raised very important ethical concerns in both the scientific community and with the public at large.

A special report can be found on this page titled: Utility and Morality:Contemporary Tradeoffs. Within this report there is an article by Bernard E. Rollin titled The Moral Status of Invasive Animal Research.