The goal of this project was to develop and implement a harmonized guideline for ideal and maximum dose volumes for various routes for the most common laboratory animals in biomedical research.
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3Rs
Recommended Dose Volumes for Common Laboratory Animals
Topic: Reduction
ARRIVE (Animal Research: Reporting of In Vivo Experiments) Guidelines
Our ARRIVE (Animal Research: Reporting of In Vivo Experiments) guidelines are intended to improve the reporting of research using animals – maximising information published and minimising unnecessary studies.
Topic: Reduction
Searching for 3Rs Information - Published Literature Sources
The I3R group produced the first edition of this document in January 2001 to assist researches and information professionals in the pharmaceutical industry.
Topic: Reduction
3Rs Reduction
This site provides an interactive short course on experimental design for research scientists working with laboratory animals. The aim is to reduce the number of animals which are used, improve the quality of the science and save time, money and other scientific resources.
Topic: Reduction
Collaborative Approach to Metanalysis
CAMARADES provides a supporting framework for groups involved in the systematic review and meta-analysis of data.
Topic: Reduction
General Database Information
EURL ECVAM
The EURL ECVAM DataBase service on ALternative Methods (DB-ALM).
Topic: Alternative methods, Information on drugs and diseases
NORINA (A Norwegian Inventory of Alternatives)
NORINA is an English-language database containing information on over 3,500 audiovisual aids that may be used as alternatives or supplements to the use of animals in education and training, including dissection alternatives, at all levels from Junior School to University. The information in the database has been collected from 1991 onwards.
Topic: Alternative methods, Search tools and databases
ECVAM QSAR Model Inventory
EURL ECVAM QSAR Model Inventory of the Commission’s Joint Research Centre (JRC).
Topic: Alternative methods
European Consensus-Platform for Alternatives (ECOPA)
Topic: Alternative methods
Fund for the Replacement of Animals in Medical Experiments (FRAME)
Topic: Alternative methods
Alternatives-NIH-USA-ICCVAM
Topic: Alternative methods