"The Design of Animal Experiments" is intended for all research scientists who use laboratory animals, with the aim of helping them to design their own experiments more effectively.
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3Rs
The Design of Animal Experiments
Topic: Reduction
Isogenic Strains
Isogenic strains (inbred strains and F1 hybrids) are like immortal clones of genetically identical individuals. The same genotype can be reproduced indefinitely. They have already made a substantial contribution to biomedical research.
Topic: Reduction
Reducing Mouse Numbers by Measuring Tumour Size Non-Invasively
Scientists at the ICR are increasingly using non-invasive methods to measure the size of tumours in mice – allowing the same mouse to be assessed several times and reducing the overall numbers
Topic: Reduction
SABRE Research UK
Systematic reviews: Evidence from animal research is considered by researchers to be of the lowest quality in medical research.
Topic: Reduction
Ex Vivo Culture Platform for Assessment of Cartilage Repair Treatment Strategies
There is a great need for valuable ex vivo models that allow for assessment of cartilage repair strategies to reduce the high number of animal experiments.
Topic: Reduction
Discipline tool
Journal of Orthopaedic Translation
Topic: Bone
Drug Discovery Today: Disease Models Bone Biology in Animal models, Including Testing of Bone Biomaterials.
Topic: Bone
General Database Information
European Consensus-Platform for Alternatives (ECOPA)
Topic: Alternative methods
Fund for the Replacement of Animals in Medical Experiments (FRAME)
Topic: Alternative methods
Alternatives-NIH-USA-ICCVAM
Topic: Alternative methods