3Rs - search page

The mission statement of the 3Rs-Centre Utrecht Life Sciences (ULS) is to stimulate the development, acceptance and implementation of methods which can Replace, Reduce and Refine (the 3Rs) animal experiments. The centre is affiliated with Utrecht Life Sciences and provides information and advice to the Animal Welfare Body of both Utrecht University and the University Medical Centre Utrecht.

Bibliography on Alternatives to Animal Testing (Altbib), is a resource portal for Alternatives to the Use of Live Vertebrates in Biomedical Research and Testing hosted by Specialized Information Services of US National Library of Medicine.

ALTBIB is a search tool that retrieves PubMed citations on alternatives to the use of live vertebrates in biomedical research and testing. It includes citations from published articles, books, book chapters, and technical reports. It also provides links to news sources and additional resources on alternatives to animal testing.

A wide variety of topics are covered, including biologics and vaccines, carcinogenesis, cytotoxicity, ecotoxicity, genotoxicity, hepatic/renal toxicity, immunotoxicity/immunology, neurotoxicity, ocular toxicity, pharmacokinetic/mechanistic studies, pyrogenicity, pulmonary toxicity, quantitative structure activity relationship (QSAR), reproductive and developmental toxicity, skin toxicity, and animal welfare.

The CAMARADES collaboration provides a supporting framework for groups involved in the systematic review and meta-analysis of data from experimental animal studies. 

Our interests range from identifying potential sources of bias in animal work; developing recommendations for improvements in the design and reporting of animal studies; developing the meta-analysis methodology the better to apply it to animal studies; through to the selection of candidate stroke drugs for clinical trial. 

CAMARADES aims to provide a central focus for data sharing; to act as a resource for those wishing to carry out such reviews; to provide a web based stratified meta-analysis bioinformatics engine (under development!); and to act as a repository for completed reviews.

CAAT is an academic, science based centre within the John Hopkins Bloomberg School of Public Health in the USA and the University of Konstanz in Germany which is  dedicated to the promotion of research intoin vitro and other alternative techniques, Three Rs education and information.

Consensus meetings on the care and use of fish, wildlife and agricultural animals in research is provided by Norecopa. It contains presentations, guidelines and consensus statements from four international meetings covering all Three Rs, is in English and free of charge.

AMC Tool is a programme to calculate antimicrobial consumption. It is aimed to replace the old ABC Calc tool.