The Medicines Evaluation Board assesses and monitors the efficacy, risks and quality of human and veterinary medicines, and the safety of novel foods for human consumption.
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General Database Information
The Interspecies Database helps researchers to make an optimal choice of species and strain of the animal model, which is essential for efficient extrapolation of animal data to humans or other animals. Thee database has initially been developed by the National Institute for Public Health and the Environment (RIVM) and the Dutch Ministry of Health, Welfare and Sports. It is offered by the 3Rs-Centre ULS in collaboration with the RIVM.
CAAT is an academic, science based centre within the John Hopkins Bloomberg School of Public Health in the USA and the University of Konstanz in Germany which is dedicated to the promotion of research intoin vitro and other alternative techniques, Three Rs education and information.
ICLAS is an international scientific organization dedicated to advancing human and animal health by promoting the ethical care and use of laboratory animals in research worldwide.
The mission statement of the 3Rs-Centre Utrecht Life Sciences (ULS) is to stimulate the development, acceptance and implementation of methods which can Replace, Reduce and Refine (the 3Rs) animal experiments. The centre is affiliated with Utrecht Life Sciences and provides information and advice to the Animal Welfare Body of both Utrecht University and the University Medical Centre Utrecht.
CCAC promotes the application of Three Rs in Canada. Through a website it provides the latest information on the Three Rs, a search tool and a search guide.
ALTBIB is a search tool that retrieves PubMed citations on alternatives to the use of live vertebrates in biomedical research and testing. It includes citations from published articles, books, book chapters, and technical reports. It also provides links to news sources and additional resources on alternatives to animal testing.
A wide variety of topics are covered, including biologics and vaccines, carcinogenesis, cytotoxicity, ecotoxicity, genotoxicity, hepatic/renal toxicity, immunotoxicity/immunology, neurotoxicity, ocular toxicity, pharmacokinetic/mechanistic studies, pyrogenicity, pulmonary toxicity, quantitative structure activity relationship (QSAR), reproductive and developmental toxicity, skin toxicity, and animal welfare.