3Rs - search page

The mission statement of the 3Rs-Centre Utrecht Life Sciences (ULS) is to stimulate the development, acceptance and implementation of methods which can Replace, Reduce and Refine (the 3Rs) animal experiments. The centre is affiliated with Utrecht Life Sciences and provides information and advice to the Animal Welfare Body of both Utrecht University and the University Medical Centre Utrecht.

ALTBIB is a search tool that retrieves PubMed citations on alternatives to the use of live vertebrates in biomedical research and testing. It includes citations from published articles, books, book chapters, and technical reports. It also provides links to news sources and additional resources on alternatives to animal testing.

A wide variety of topics are covered, including biologics and vaccines, carcinogenesis, cytotoxicity, ecotoxicity, genotoxicity, hepatic/renal toxicity, immunotoxicity/immunology, neurotoxicity, ocular toxicity, pharmacokinetic/mechanistic studies, pyrogenicity, pulmonary toxicity, quantitative structure activity relationship (QSAR), reproductive and developmental toxicity, skin toxicity, and animal welfare.

AMC Tool is a programme to calculate antimicrobial consumption. It is aimed to replace the old ABC Calc tool.

Database on alternatives on the internat-Zebet- One of the tasks of ZEBET is to provide scientists from industry, universities and public authorities with information on alternative methods in a database developed for that specific purpose. Since February 2000 the ZEBET database on alternative methods to animal experiments has been accessible without license fees on the Internet in German and English through the German Institute for Medical Documentation and Information (DIMDI). Please note this website is no longer updated. This is a resource only.

Recommendations for Excellence: as part of ongoing efforts to reduce waste and increase the reproducibility of animal research and testing, a group of experts led by the Secretary of Norecopa has produced a set of guidelines for planning animal experiments

The mission of the Centre is to provide leadership in matters relevant to animal welfare, focusing on the appropriate and humane care, husbandry, and management of animals.