The Medicines Evaluation Board assesses and monitors the efficacy, risks and quality of human and veterinary medicines, and the safety of novel foods for human consumption.
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General Database Information
The mission statement of the 3Rs-Centre Utrecht Life Sciences (ULS) is to stimulate the development, acceptance and implementation of methods which can Replace, Reduce and Refine (the 3Rs) animal experiments. The centre is affiliated with Utrecht Life Sciences and provides information and advice to the Animal Welfare Body of both Utrecht University and the University Medical Centre Utrecht.
Laboratory Animals is an international journal of laboratory animal science and welfare. Laboratory Animals publishes peer-reviewed original papers and reviews on all aspects of the use of animals in biomedical research. The journal promotes improvements in the welfare or well-being of the animals used, it particularly focuses on research that reduces the number of animals used or which replaces animal models with in vitro alternatives.
Laboratory Animals publishes papers dealing with all aspects of the use of animals in biomedical research, including: new animal models; laboratory animal microbiology; clinical case reports; descriptions of new or improved research techniques; reports on the influence of environmental and other variables on research results; descriptions of techniques which offer replacements for in vivo models; and basic data characterizing the haematology, biochemistry or pathology of new or existing animal models. Papers describing work which involves a reduction in the number of animals that need to be used; or which replace animals with in vitro alternatives; or which represent a significant refinement in methodology, leading to improvements in the welfare or wellbeing of the animals used, are especially encouraged.
The Interspecies Database helps researchers to make an optimal choice of species and strain of the animal model, which is essential for efficient extrapolation of animal data to humans or other animals. Thee database has initially been developed by the National Institute for Public Health and the Environment (RIVM) and the Dutch Ministry of Health, Welfare and Sports. It is offered by the 3Rs-Centre ULS in collaboration with the RIVM.
Journal of Applied Animal Welfare Science (JAAWS) is a US journal that publishes articles, commentaries, and brief research reports on methods of experimentation, husbandry and care that demonstrably enhance the welfare of all nonhuman animals.
The Allen Brain Observatory presents the first standardized in vivo survey of physiological activity in the mouse visual cortex, featuring representations of visually evoked calcium responses from GCaMP6-expressing neurons in selected cortical layers, visual areas and Cre lines.