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3Rs

Isogenic Strains

Isogenic strains (inbred strains and F1 hybrids) are like immortal clones of genetically identical individuals. The same genotype can be reproduced indefinitely. They have already made a substantial contribution to biomedical research. 

Topic: Reduction

Reducing Mouse Numbers by Measuring Tumour Size Non-Invasively

Scientists at the ICR are increasingly using non-invasive methods to measure the size of tumours in mice – allowing the same mouse to be assessed several times and reducing the overall numbers

Topic: Reduction

SABRE Research UK

Systematic reviews: Evidence from animal research is considered by researchers to be of the lowest quality in medical research.

Topic: Reduction

Ex Vivo Culture Platform for Assessment of Cartilage Repair Treatment Strategies

There is a great need for valuable ex vivo models that allow for assessment of cartilage repair strategies to reduce the high number of animal experiments.

Topic: Reduction

New Tools for The Generation of peptide- and Antibody-Based Ligands in Vitro: Reduction of Antibody Production in Experimental Animals
Topic: Reduction

General Database Information

EURL ECVAM

The EURL ECVAM DataBase service on ALternative Methods (DB-ALM).

Topic: Alternative methods, Information on drugs and diseases

Toxicology Data Network

Toxicology Data Network- is a group of databases covering chemicals and drugs, diseases and the environment, environmental health, occupational safety and health, poisoning, risk assessment and regulations, and toxicology.

Topic: Information on drugs and diseases

International Society for Pharmacoepidemiology (ISPE)
Topic: Information on drugs and diseases

NORINA (A Norwegian Inventory of Alternatives)

NORINA is an English-language database containing information on over 3,500 audiovisual aids that may be used as alternatives or supplements to the use of animals in education and training, including dissection alternatives, at all levels from Junior School to University.  The information in the database has been collected from 1991 onwards.

Topic: Alternative methods, Search tools and databases

EMBASE from Elsevier Life Science Solutions

Embase is a crucial resource for discovering biomedical evidence within published, peer-reviewed literature, in-press publications and conference abstracts.

Topic: Information on drugs and diseases

Norwegian Institute of Public Health

Researchers can apply for access to data from health registries and health studies, as well as biological material from the biobanks. Here you will find guidelines and electronic application forms.

Topic: Information on drugs and diseases

ECVAM QSAR Model Inventory

EURL ECVAM QSAR Model Inventory of the Commission’s Joint Research Centre (JRC).

Topic: Alternative methods

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