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NC3Rs-New Device for Refined Neural Recording in Mice Could Transform Dementia Research

Research published in Scientific Reports describes a new ultra lightweight system for recording neural activity in the brains of mice.

Topic: Aged

MouseAGE

MouseAGE is opening a call for European researchers to establish their infrastructure needs in the area of ageing and age-related disorders at the preclinical stage with a view to coordinate efforts for applications for funding.

Topic: Aged

General Database Information

Medicines Evaluations Board

The Medicines Evaluation Board assesses and monitors the efficacy, risks and quality of human and veterinary medicines, and the safety of novel foods for human consumption.

Topic: Information on drugs and diseases

Welcome to the Node

Welcome to the Node: the community site for and by developmental biologists. The Node is a place for you to share news from the developmental biology community, to discuss relevant topics or just see what’s new. And you can do more than reading – we are a community site, so anyone can post on the Node after creating an account. The Node is run by the journal Development and its publisher, The Company of Biologists. We get around 20,000 visitors per month, and typically publish one post per day.

 

Topic: Portals and Websites

The Interspecies Database

The Interspecies Database helps researchers to make an optimal choice of species and strain of the animal model, which is essential for efficient extrapolation of animal data to humans or other animals. Thee database has initially been developed by the National Institute for Public Health and the Environment (RIVM) and the Dutch Ministry of Health, Welfare and Sports. It is offered by the 3Rs-Centre ULS in collaboration with the RIVM.

Topic: Information on drugs and diseases

ALTWEB-Alternatives to Animal Testing
Topic: Alternative methods

Bibliography on Alternatives to Animal Testing (Altbib)

Bibliography on Alternatives to Animal Testing (Altbib), is a resource portal for Alternatives to the Use of Live Vertebrates in Biomedical Research and Testing hosted by Specialized Information Services of US National Library of Medicine.

Topic: Portals and Websites

WHO Collaborating Centre for Drug Statistics Methodology
Topic: Information on drugs and diseases

CAMARADES

The CAMARADES collaboration provides a supporting framework for groups involved in the systematic review and meta-analysis of data from experimental animal studies. 

Our interests range from identifying potential sources of bias in animal work; developing recommendations for improvements in the design and reporting of animal studies; developing the meta-analysis methodology the better to apply it to animal studies; through to the selection of candidate stroke drugs for clinical trial. 

CAMARADES aims to provide a central focus for data sharing; to act as a resource for those wishing to carry out such reviews; to provide a web based stratified meta-analysis bioinformatics engine (under development!); and to act as a repository for completed reviews.

Topic: Other Resources

Altbib-Bibliography on Alternatives to Animal Testing

ALTBIB is a search tool that retrieves PubMed citations on alternatives to the use of live vertebrates in biomedical research and testing. It includes citations from published articles, books, book chapters, and technical reports. It also provides links to news sources and additional resources on alternatives to animal testing.

A wide variety of topics are covered, including biologics and vaccines, carcinogenesis, cytotoxicity, ecotoxicity, genotoxicity, hepatic/renal toxicity, immunotoxicity/immunology, neurotoxicity, ocular toxicity, pharmacokinetic/mechanistic studies, pyrogenicity, pulmonary toxicity, quantitative structure activity relationship (QSAR), reproductive and developmental toxicity, skin toxicity, and animal welfare.

Topic: Alternative methods

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