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3Rs

ARRIVE (Animal Research: Reporting of In Vivo Experiments) Guidelines

Our ARRIVE (Animal Research: Reporting of In Vivo Experiments) guidelines are intended to improve the reporting of research using animals – maximising information published and minimising unnecessary studies.

Topic: Reduction

Searching for 3Rs Information - Published Literature Sources

The I3R group produced the first edition of this document in January 2001 to assist researches and information professionals in the pharmaceutical industry.  

Topic: Reduction

3Rs Reduction

This site provides an interactive short course on experimental design for research scientists working with laboratory animals. The aim is to reduce the number of animals which are used, improve the quality of the science and save time, money and other scientific resources.

Topic: Reduction

Collaborative Approach to Metanalysis

CAMARADES provides a supporting framework for groups involved in the systematic review and meta-analysis of data.

Topic: Reduction

PREPARE (Planning Research and Experimental Procedures on Animals: Recommendations for Excellence)
Topic: Reduction

General Database Information

Fund for the Replacement of Animals in Medical Experiments (FRAME)
Topic: Alternative methods

The Biosciences Federation Animal Science Group

The Biosciences Federation Animal Science Group was established in December 2002 and launched in September 2003 as an umbrella organisation to promote interaction within the biosciences community, particularly in areas of research and teaching; to provide information to assist the formulation of scientific policy; and, perhaps most challenging of all, to debate the ethical issues surrounding recent advances in the biosciences (see previous report by Nancy Rothwell).

Topic: Ethics

Alternatives-NIH-USA-ICCVAM
Topic: Alternative methods

NC3Rs- National Centre for the Replacement Refinement and Reduction of Animals in Research
Topic: Ethics

ALTWEB-Alternatives to Animal Testing
Topic: Alternative methods

Nuffield Bioethics

The issues addressed in this Report have been a subject of intense public debate over at least the past four hundred years. Feelings are strong on all sides of the issues, and in recent years reports of violent action against those conducting animal research in the UK have brought the matter to the forefront of public attention.

Topic: Ethics

Altbib-Bibliography on Alternatives to Animal Testing

ALTBIB is a search tool that retrieves PubMed citations on alternatives to the use of live vertebrates in biomedical research and testing. It includes citations from published articles, books, book chapters, and technical reports. It also provides links to news sources and additional resources on alternatives to animal testing.

A wide variety of topics are covered, including biologics and vaccines, carcinogenesis, cytotoxicity, ecotoxicity, genotoxicity, hepatic/renal toxicity, immunotoxicity/immunology, neurotoxicity, ocular toxicity, pharmacokinetic/mechanistic studies, pyrogenicity, pulmonary toxicity, quantitative structure activity relationship (QSAR), reproductive and developmental toxicity, skin toxicity, and animal welfare.

Topic: Alternative methods

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