3Rs - search page

Humane Endpoints Website is provided by 3Rs-Centre Utrecht Life Sciences, gives insight into the recognition and application of humane endpoints in rodents. The website contributes to refinement, the prevention of unnecessary suffering in laboratory animals, by offering information, videos and photographs of rodent species. In addition, the website provides free training modules (accessible after registration). The site is currently available in EN, NL and FR. DE and ES will follow soon.

The Biosciences Federation Animal Science Group was established in December 2002 and launched in September 2003 as an umbrella organisation to promote interaction within the biosciences community, particularly in areas of research and teaching; to provide information to assist the formulation of scientific policy; and, perhaps most challenging of all, to debate the ethical issues surrounding recent advances in the biosciences (see previous report by Nancy Rothwell).

The aim of "InVitroJobs" is to enable researchers to access this branch of research more easily. Alongside the job search portal, the site maintains an up-to-date list of research groups active in the development of animal-free techniques. The primary aims of this list are to advertise job vacancies, to provide students with the opportunity to contact these research groups directly to obtain information for thesis assignments and to promote cooperation, networking and the exchange of ideas between researchers. 

A mainly government funded body which provides input to the UK’s Three Rs agenda, carries out research and provides funds for Three R research. 

The issues addressed in this Report have been a subject of intense public debate over at least the past four hundred years. Feelings are strong on all sides of the issues, and in recent years reports of violent action against those conducting animal research in the UK have brought the matter to the forefront of public attention.

ALTBIB is a search tool that retrieves PubMed citations on alternatives to the use of live vertebrates in biomedical research and testing. It includes citations from published articles, books, book chapters, and technical reports. It also provides links to news sources and additional resources on alternatives to animal testing.

A wide variety of topics are covered, including biologics and vaccines, carcinogenesis, cytotoxicity, ecotoxicity, genotoxicity, hepatic/renal toxicity, immunotoxicity/immunology, neurotoxicity, ocular toxicity, pharmacokinetic/mechanistic studies, pyrogenicity, pulmonary toxicity, quantitative structure activity relationship (QSAR), reproductive and developmental toxicity, skin toxicity, and animal welfare.

TSAR is a tool aimed at providing a transparent view on the status of alternative methods as they progress from purely scientific protocols submitted for eventual validation to being actively used in a regulatory context. This tracking system intends to cover all steps, from the initial submission for validation until final adoption by inclusion in the EU legislation and/or related Guidance Documents, when appropriate.