The issues addressed in this Report have been a subject of intense public debate over at least the past four hundred years. Feelings are strong on all sides of the issues, and in recent years reports of violent action against those conducting animal research in the UK have brought the matter to the forefront of public attention.
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General Database Information
ALTBIB is a search tool that retrieves PubMed citations on alternatives to the use of live vertebrates in biomedical research and testing. It includes citations from published articles, books, book chapters, and technical reports. It also provides links to news sources and additional resources on alternatives to animal testing.
A wide variety of topics are covered, including biologics and vaccines, carcinogenesis, cytotoxicity, ecotoxicity, genotoxicity, hepatic/renal toxicity, immunotoxicity/immunology, neurotoxicity, ocular toxicity, pharmacokinetic/mechanistic studies, pyrogenicity, pulmonary toxicity, quantitative structure activity relationship (QSAR), reproductive and developmental toxicity, skin toxicity, and animal welfare.
Species specific
General information collated to help with the implementation of approaches to reduce and refine the use of GA mice.
A key aim of the Group is to encourage people to take account of the whole lifetime experience of laboratory rodents, ensuring that every potential impact on their wellbeing has been reviewed and refined.
genOway offers industry scientists immediate access to EUCOMM conditional KO mouse models.
The booklet is aimed at anyone working with or caring for GA animals, those responsible for recording or maintaining records of GA animals, and/or those involved in the import, export or transport of GA animals.
This page provides access to searchable, hypertext listings of inbred strains of mice and inbred strains of rats. Both sets of information were provided by Dr. Michael FW Festing (MRC Toxicology Unit) and were converted for Web presentation by the Mouse Genome Informatics Group at The Jackson Laboratory.
In 2006, the Transgenic Training Working Group (TTWG) was formed to identify and provide specific training for carers and users of genetically altered animals.