3Rs - search page

The Foundation for Liver Research UK was established in 1974 to develop and extend research into diseases of the human liver and to enhance medical research generally.

CLDF supports a wide range of projects, including clinical and laboratory-based research, lately moving into social research which looks at topics such as how to improve quality of life. 

The official journal of the Institute of Animal Technology and of the European Federation of Animal Technologists (EFAT).Animal Technology and Welfare aims to be the medium for animal technologists and all those concerned with the care and welfare of animals used for research purposes to communicate ‘best practice. ATW especially aims to promote and develop the 3Rs particularly in respect of Refinement.

More importantly, ATW promotes the generally accepted ‘4th R’, Responsibility. The responsibility that all animal technologists have in ensuring dissemination of ‘best practice’ to every institution using animals in research. ATW enjoys a unique position as the scientific publication for the leading organisations (IAT and EFAT) for the welfare of animals in research.

The issues addressed in this Report have been a subject of intense public debate over at least the past four hundred years. Feelings are strong on all sides of the issues, and in recent years reports of violent action against those conducting animal research in the UK have brought the matter to the forefront of public attention.

ALTBIB is a search tool that retrieves PubMed citations on alternatives to the use of live vertebrates in biomedical research and testing. It includes citations from published articles, books, book chapters, and technical reports. It also provides links to news sources and additional resources on alternatives to animal testing.

A wide variety of topics are covered, including biologics and vaccines, carcinogenesis, cytotoxicity, ecotoxicity, genotoxicity, hepatic/renal toxicity, immunotoxicity/immunology, neurotoxicity, ocular toxicity, pharmacokinetic/mechanistic studies, pyrogenicity, pulmonary toxicity, quantitative structure activity relationship (QSAR), reproductive and developmental toxicity, skin toxicity, and animal welfare.

Guiding principles on good practice for Animal Welfare and Ethical Review Bodies (2015) (PDF 1.76MB). Developed and published jointly by the RSPCA and the Laboratory Animal Science Association (LASA), this resource aims to help in the efficient and effective operation of local animal welfare and ethical review bodies.

Database on alternatives on the internat-Zebet- One of the tasks of ZEBET is to provide scientists from industry, universities and public authorities with information on alternative methods in a database developed for that specific purpose. Since February 2000 the ZEBET database on alternative methods to animal experiments has been accessible without license fees on the Internet in German and English through the German Institute for Medical Documentation and Information (DIMDI). Please note this website is no longer updated. This is a resource only.