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The use of animals in research, teaching and testing is an important ethical and political issue. Much of the discussion about this issue revolves around the relative value, often referred to as 'moral value', of humans and animals.

EURL ECVAM QSAR Model Inventory of the Commission’s Joint Research Centre (JRC).

Over the past twenty years or so, there has been a ‘revolution’ in the life sciences,and our knowledge and capabilities have dramatically increased. At the same time, these advances have raised very important ethical concerns in both the scientific community and with the public at large.

ARRIVE (Animal Research: Reporting of In Vivo Experiments) guidelines are intended to improve the reporting of research using animals – maximising information published and minimising unnecessary studies.

A special report can be found on this page titled: Utility and Morality:Contemporary Tradeoffs. Within this report there is an article by Bernard E. Rollin titled The Moral Status of Invasive Animal Research.

The Academy is working to address all aspects of animals in research, from engaging in debate about how to regulate the use of animals in research, to efforts to improve the openness of organisations that are involved in animal research.

The Biosciences Federation Animal Science Group was established in December 2002 and launched in September 2003 as an umbrella organisation to promote interaction within the biosciences community, particularly in areas of research and teaching; to provide information to assist the formulation of scientific policy; and, perhaps most challenging of all, to debate the ethical issues surrounding recent advances in the biosciences (see previous report by Nancy Rothwell).

The CAMARADES collaboration provides a supporting framework for groups involved in the systematic review and meta-analysis of data from experimental animal studies. 

Our interests range from identifying potential sources of bias in animal work; developing recommendations for improvements in the design and reporting of animal studies; developing the meta-analysis methodology the better to apply it to animal studies; through to the selection of candidate stroke drugs for clinical trial. 

CAMARADES aims to provide a central focus for data sharing; to act as a resource for those wishing to carry out such reviews; to provide a web based stratified meta-analysis bioinformatics engine (under development!); and to act as a repository for completed reviews.