Over the last two years, representatives from the UK’s stroke research community have been working, in a collaboration led by the NC3Rs, to improve the welfare and increase the scientific value of rodent models of stroke. The findings from the collaboration - The IMPROVE Guidelines (Ischaemia Models: Procedural Refinements Of in Vivo Experiments) have been published in the Journal of Cerebral Bloodflow and Metabolism.
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IMPROVE-ing Animal Welfare in Experimental Stroke Research
Topic: Cardiology
Jax Phenotype-Cardiovascular
Topic: Cardiology
Liverpool University Vetschool Cardiology Department
Topic: Cardiology
Penn Vet School Cardiology Research
Topic: Cardiology
Journal of Veterinary Cardiology
Topic: Cardiology
Animal Research in Pediatric Cardiology and Cardiac Surgery Paper and Pediatric Journal
Topic: Cardiology
JACC: Cardiovascular Interventions Open Access Journal
Topic: Cardiology
General Database Information
CAAT-Europe (Centre of Alternatives to Animal Testing)
Topic: Alternative methods, Information on drugs and diseases
Fund for the Replacement of Animals in Medical Experiments (FRAME)
FRAME is dedicated to the development of new and valid methods that will replace the need for laboratory animals in medical and scientific research, education, and testing. Where the use of animals is currently necessary, FRAME supports the reduction of numbers involved to an unavoidable minimum and refinement of experimental procedures to minimise any suffering caused. The E-learning resource of FRAME has been set up to provide teachers, school children, students and general supporters with information about the different areas of animal experimentation and with specific resources as to how it can be reduced, refined or replaced.
Topic: Portals and Websites
Database on alternatives on the Internat-Zebet
Database on alternatives on the internat-Zebet- One of the tasks of ZEBET is to provide scientists from industry, universities and public authorities with information on alternative methods in a database developed for that specific purpose. Since February 2000 the ZEBET database on alternative methods to animal experiments has been accessible without license fees on the Internet in German and English through the German Institute for Medical Documentation and Information (DIMDI). Please note this website is no longer updated. This is a resource only.
Topic: Alternative methods
UCDavis Centre for Animal Alternatives Information
The mission of the Centre is to provide leadership in matters relevant to animal welfare, focusing on the appropriate and humane care, husbandry, and management of animals.
Topic: Alternative methods
Humane Endpoints Website
Humane Endpoints Website is provided by 3Rs-Centre Utrecht Life Sciences, gives insight into the recognition and application of humane endpoints in rodents. The website contributes to refinement, the prevention of unnecessary suffering in laboratory animals, by offering information, videos and photographs of rodent species. In addition, the website provides free training modules (accessible after registration). The site is currently available in EN, NL and FR. DE and ES will follow soon.
Topic: Portals and Websites