3Rs - search page

The FRAME lab uses cells derived from human tissues to produce biologically relevant in vitro models of human organs, which behave and respond in the way they would in the body.

A website with explanations and sources of alternatives.

Internet platform for animal free research (German site).

Separate page from this German site- in the table you will find a selection of foundations and organisations in alphabetical order which support the development of non-animal methods of research with awards.

Sabre offers ten recommendations and a strategy.They define these reccomendations (the 10Rs+) as RESPOND, REPLICATE, REGISTER, REPORT, RECORD, REVIEW, REGULATE, REAPPRAISE, RATIONALISE, REINVENT, REPRESENT. A word document with further information on the 10Rs+ (in a table) is available to download at the bottom of the page.

This section contains a selection of resources highlighting the alternatives to using animals in research, testing and teaching.

Establishment of a novel system for the production of large numbers of mouse basophils in vitro.

Appendix A of the Animal Usage Form asks for the methods used to search for alternatives to procedures that may cause more than slight pain or distress to animals.

The RSPCA list a number of Alternative approaches: the use of isolated cells and tissues, using computers and mathematics to model biological processes and predict the effects of chemicals and drugs, designing ways of doing experiments safely in human volunteers, using simple organisms, such as bacteria, to study basic biological processes
exploring new advanced technologies such as robotics, molecular techniques, tissue engineering and "organs-on-microchips", not doing the experiment at all is one option - we encourage greater consideration of whether animal use could be avoided through more critical ethical review.

Below are articles on the subject of Alternatives. If you can't see what you are looking for other categories are displayed on the left under 'Our Quick Links'.

This roadmap, vision and strategy for non-animal technologies in the UK has been drawn up by Innovate UK, the National Centre for the Replacement Refinement and Reduction of Animals in Research, the Biotechnology and Biological Sciences Research Council, the Defence, Science and Technology Laboratory, the Engineering and Physical Sciences Research Council and the Medical Research Council, and has been published on their behalf by Innovate UK. It is intended to guide the efforts of all those working in this area. The issues outlined and the recommendations have come out of extensive discussions between the six organisations that are endorsing the roadmap and with many other key stakeholders.