3Rs - search page

Journal of Applied Animal Welfare Science (JAAWS) is a US journal that publishes articles, commentaries, and brief research reports on methods of experimentation, husbandry and care that demonstrably enhance the welfare of all nonhuman animals.

The official journal of the Institute of Animal Technology and of the European Federation of Animal Technologists (EFAT).Animal Technology and Welfare aims to be the medium for animal technologists and all those concerned with the care and welfare of animals used for research purposes to communicate ‘best practice. ATW especially aims to promote and develop the 3Rs particularly in respect of Refinement.

More importantly, ATW promotes the generally accepted ‘4th R’, Responsibility. The responsibility that all animal technologists have in ensuring dissemination of ‘best practice’ to every institution using animals in research. ATW enjoys a unique position as the scientific publication for the leading organisations (IAT and EFAT) for the welfare of animals in research.

Welcome to the Node: the community site for and by developmental biologists. The Node is a place for you to share news from the developmental biology community, to discuss relevant topics or just see what’s new. And you can do more than reading – we are a community site, so anyone can post on the Node after creating an account. The Node is run by the journal Development and its publisher, The Company of Biologists. We get around 20,000 visitors per month, and typically publish one post per day.

Three Rs Resources

The Australian and New Zealand Council for the Care of Animals in Research and Teaching (ANZCCART) and the Ministry for Primary Industries have produced a series of booklets on the application of the three Rs (replacement, reduction and refinement) in the use of animals in research and teaching.

• Cell-based Disease Models (replacement)
• Computer Assisted Learning (replacement)
• Mannequins and Dummies (replacement)
• Alternatives to shellfish toxicity testing (replacement) 
• Fireflies to the rescue (reduction)
• Mathematical models (reduction)
• Tissue sharing (reduction)
• Simple ingenuity (refinement)
• Non-Invasive Methods (refinement)
• Living syringes (refinement)
• Oil emulsified gels (refinement)

The use of animals in medical and pharmaceutical research is essential to the understanding of disease and the safe development of medicines.

This page provides access to searchable, hypertext listings of inbred strains of mice and inbred strains of rats. Both sets of information were provided by Dr. Michael FW Festing (MRC Toxicology Unit) and were converted for Web presentation by the Mouse Genome Informatics Group at The Jackson Laboratory.

The Sanger Institute started the zebrafish genome sequencing project in 2001 and has generated several genome assemblies of the Tuebingen strain. After the release of Zv9, the zebrafish genome project joined the Genome Reference Consortium (GRC) for further improvement and ongoing maintenance. The GRC has now released a new reference assembly, GRCz11.

The Sanger Mouse Genetics Programme (Sanger MGP) was initiated in 2006 to advance the functional understanding of protein coding and non-coding RNA genes using a standardised high-throughput phenotypic screen designed to contribute to improved diagnosis and treatment of human disease.

INFRAFRONTIER aims to build a world-class research infrastructure that provides the biomedical research community with the tools needed to unravel the role of gene function in human disease.

General information collated to help with the implementation of approaches to reduce and refine the use of GA mice.