3Rs - search page

This Website was created to serve as a gateway to alternatives news, information, and resources on the Internet and beyond. Altweb hosts the journal ALTEX: Alternatives to Animal Experimentation, which is the official publication of the Johns Hopkins Center for Alternatives to Animal Testing (CAAT).

Welcome to the Node: the community site for and by developmental biologists. The Node is a place for you to share news from the developmental biology community, to discuss relevant topics or just see what’s new. And you can do more than reading – we are a community site, so anyone can post on the Node after creating an account. The Node is run by the journal Development and its publisher, The Company of Biologists. We get around 20,000 visitors per month, and typically publish one post per day.

In collaboration with the Animal Welfare Information Center at the US Department of Agriculture in Beltsville, USA has produced a database which provides an overview of guidelines, databases, journals, email lists, regulations and policies which may help researchers to implement the 3Rs when planning research that may involve animals. The database is called 3R Guide.

The aim of 3R Guide is to provide a 'one-stop shop' for researchers who need to gain an overview of available 3R resources.

Bibliography on Alternatives to Animal Testing (Altbib), is a resource portal for Alternatives to the Use of Live Vertebrates in Biomedical Research and Testing hosted by Specialized Information Services of US National Library of Medicine.

NORINA is an English-language database containing information on over 3,500 audiovisual aids that may be used as alternatives or supplements to the use of animals in education and training, including dissection alternatives, at all levels from Junior School to University.  The information in the database has been collected from 1991 onwards.

CAAT is an academic, science based centre within the John Hopkins Bloomberg School of Public Health in the USA and the University of Konstanz in Germany which is  dedicated to the promotion of research intoin vitro and other alternative techniques, Three Rs education and information.

The Classic AVs database complements NORINA by providing information on audiovisual products produced some years ago, using technology which has been surpassed by modern digital techniques. We offer this collection for those who wish to continue to use classic technology.

CCAC promotes the application of Three Rs in Canada. Through a website it provides the latest information on the Three Rs,   a search tool and a search guide. 

EU 3Rs databases-The protection and welfare of animals is an area covered by a wide range of EU legislation. This includes the protection of wildlife, zoo animals, farm animals, animals in transport and animals used for scientific purposes. Animal studies, whether for the development or production of new medicines, for physiological studies, for studying environmental effects or for the testing of chemicals or new food additives, has to be carried out in compliance with EU legislation. 

Welcome to the Experimental Design Assistant, a free resource from the NC3Rs to support researchers in the planning of animal experiments - ensuring robust study design and reliable and reproducible findings.

The EDA consists of a web application and a supporting website; benefits include:
•The ability to build a stepwise visual representation of your experiment
•Feedback and advice on your experimental plan 
•Dedicated support for randomisation, blinding and sample size calculation
•Practical information to improve knowledge of experimental design
•Improved transparency of your experimental design, allowing you to share and discuss your plan with colleagues and collaborators

FRAME is dedicated to the development of new and valid methods that will replace the need for laboratory animals in medical and scientific research, education, and testing. Where the use of animals is currently necessary, FRAME supports the reduction of numbers involved to an unavoidable minimum and refinement of experimental procedures to minimise any suffering caused. The E-learning resource of FRAME has been set up to provide teachers, school children, students and general supporters with information about the different areas of animal experimentation and with specific resources as to how it can be reduced, refined or replaced. 

 Find Human tissue samples online using the UKCRC Tissue Directory.