3Rs - search page

EU 3Rs databases-The protection and welfare of animals is an area covered by a wide range of EU legislation. This includes the protection of wildlife, zoo animals, farm animals, animals in transport and animals used for scientific purposes. Animal studies, whether for the development or production of new medicines, for physiological studies, for studying environmental effects or for the testing of chemicals or new food additives, has to be carried out in compliance with EU legislation. 

Welcome to the Experimental Design Assistant, a free resource from the NC3Rs to support researchers in the planning of animal experiments - ensuring robust study design and reliable and reproducible findings.

The EDA consists of a web application and a supporting website; benefits include:
•The ability to build a stepwise visual representation of your experiment
•Feedback and advice on your experimental plan 
•Dedicated support for randomisation, blinding and sample size calculation
•Practical information to improve knowledge of experimental design
•Improved transparency of your experimental design, allowing you to share and discuss your plan with colleagues and collaborators

Laboratory Animals is an international journal of laboratory animal science and welfare. Laboratory Animals publishes peer-reviewed original papers and reviews on all aspects of the use of animals in biomedical research. The journal promotes improvements in the welfare or well-being of the animals used, it particularly focuses on research that reduces the number of animals used or which replaces animal models with in vitro alternatives.

Laboratory Animals publishes papers dealing with all aspects of the use of animals in biomedical research, including: new animal models; laboratory animal microbiology; clinical case reports; descriptions of new or improved research techniques; reports on the influence of environmental and other variables on research results; descriptions of techniques which offer replacements for in vivo models; and basic data characterizing the haematology, biochemistry or pathology of new or existing animal models. Papers describing work which involves a reduction in the number of animals that need to be used; or which replace animals with in vitro alternatives; or which represent a significant refinement in methodology, leading to improvements in the welfare or wellbeing of the animals used, are especially encouraged.

 Find Human tissue samples online using the UKCRC Tissue Directory.

This section of the Three Rs microsite provides useful links and information to help visitors easily find a wide range of resources.

Journal of Applied Animal Welfare Science (JAAWS) is a US journal that publishes articles, commentaries, and brief research reports on methods of experimentation, husbandry and care that demonstrably enhance the welfare of all nonhuman animals.

By generating and making public data that indicates how cells respond to various genetic and environmental stressors, the LINCS project will help us gain a more detailed understanding of cell pathways and aid efforts to develop therapies.

Welcome to the Zika experimental science team (ZEST) data portal. Given the urgency of the ongoing Zika virus epidemic, we are making our study results available in real-time. Each study and its available data are shown.

This website appears to be temporarily unavailable. 6th October 2023

The official journal of the Institute of Animal Technology and of the European Federation of Animal Technologists (EFAT).Animal Technology and Welfare aims to be the medium for animal technologists and all those concerned with the care and welfare of animals used for research purposes to communicate ‘best practice. ATW especially aims to promote and develop the 3Rs particularly in respect of Refinement.

More importantly, ATW promotes the generally accepted ‘4th R’, Responsibility. The responsibility that all animal technologists have in ensuring dissemination of ‘best practice’ to every institution using animals in research. ATW enjoys a unique position as the scientific publication for the leading organisations (IAT and EFAT) for the welfare of animals in research.

Has over 5 million more abstracts than PubMed.

The Allen Brain Observatory presents the first standardized in vivo survey of physiological activity in the mouse visual cortex, featuring representations of visually evoked calcium responses from GCaMP6-expressing neurons in selected cortical layers, visual areas and Cre lines. 

PubMed comprises more than 26 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.