3Rs - search page

The IMPROVE Guidelines (Ischaemia Models: Procedural Refinements Of in Vivo Experiments) - have been published in the Journal of Cerebral Blood Flow and Metabolism

"The Design of Animal Experiments" is intended for all research scientists who use laboratory animals, with the aim of helping them to design their own experiments more effectively.

Good training in non-aversive handling has benefits for the animal, for the handler and for the reliability of data gained in experiments.

Isogenic strains (inbred strains and F1 hybrids) are like immortal clones of genetically identical individuals. The same genotype can be reproduced indefinitely. They have already made a substantial contribution to biomedical research. 

In 2008, the UFAW/RSPCA Rabbit Behaviour and Welfare Group produced a resource that sets out practical guidance on fulfilling the basic needs of the rabbit.

Collecting blood for serology testing from research animals can be a challenging process that leads to increased stress in your animal. Exclusive to Charles River, our HemaTIP™ microsampler simplifies this process by placing the collection media on the tip of an easy-to-hold stylus.

Scientists at the ICR are increasingly using non-invasive methods to measure the size of tumours in mice – allowing the same mouse to be assessed several times and reducing the overall numbers

There are several stages to consider when planning and carrying out studies involving animals to establish, implement and refine humane endpoints.

Systematic reviews: Evidence from animal research is considered by researchers to be of the lowest quality in medical research.

A resource from the research animals department on how housing and care can be refined to reduce suffering and improve welfare of animal species.

Norecopa has constructed four databases, which together with all the text on this website can be searched simultaneously using the search field at the top of every page.

There is a great need for valuable ex vivo models that allow for assessment of cartilage repair strategies to reduce the high number of animal experiments.