Blood sampling can be stressful for laboratory animals because of the handling, restraint, anaesthesia or discomfort associated with a particular technique
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3Rs
Systematic Review Facility
SyRF is a fully integrated online platform for performing systematic reviews of preclinical studies.
Topic: Reduction
RSPCA Reduce Suffering Welfare Assessment Tool
The suffering that animals experience when they are used in research and testing is a very serious concern. We believe that every possible step must be taken to reduce animal suffering to an absolute minimum.
Topic: Refinement
IMPROVE-ing animal welfare in experimental stroke research-The findings from the collaboration
The IMPROVE Guidelines (Ischaemia Models: Procedural Refinements Of in Vivo Experiments) - have been published in the Journal of Cerebral Blood Flow and Metabolism
Topic: Refinement
The Design of Animal Experiments
"The Design of Animal Experiments" is intended for all research scientists who use laboratory animals, with the aim of helping them to design their own experiments more effectively.
Topic: Reduction
Handling and Restraint-NC3Rs
Good training in non-aversive handling has benefits for the animal, for the handler and for the reliability of data gained in experiments.
Topic: Refinement
Isogenic Strains
Isogenic strains (inbred strains and F1 hybrids) are like immortal clones of genetically identical individuals. The same genotype can be reproduced indefinitely. They have already made a substantial contribution to biomedical research.
Topic: Reduction
RSPCA Refining Rabbit Welfare
In 2008, the UFAW/RSPCA Rabbit Behaviour and Welfare Group produced a resource that sets out practical guidance on fulfilling the basic needs of the rabbit.
Topic: Refinement
HemaTIP™ Microsampler
Collecting blood for serology testing from research animals can be a challenging process that leads to increased stress in your animal. Exclusive to Charles River, our HemaTIP™ microsampler simplifies this process by placing the collection media on the tip of an easy-to-hold stylus.
Topic: Refinement
Reducing Mouse Numbers by Measuring Tumour Size Non-Invasively
Scientists at the ICR are increasingly using non-invasive methods to measure the size of tumours in mice – allowing the same mouse to be assessed several times and reducing the overall numbers
Topic: Reduction
Humane Endpoints-NC3Rs
There are several stages to consider when planning and carrying out studies involving animals to establish, implement and refine humane endpoints.
Topic: Refinement
SABRE Research UK
Systematic reviews: Evidence from animal research is considered by researchers to be of the lowest quality in medical research.
Topic: Reduction