3Rs - search page

FRAME is dedicated to the development of new and valid methods that will replace the need for laboratory animals in medical and scientific research, education, and testing. Where the use of animals is currently necessary, FRAME supports the reduction of numbers involved to an unavoidable minimum and refinement of experimental procedures to minimise any suffering caused. The E-learning resource of FRAME has been set up to provide teachers, school children, students and general supporters with information about the different areas of animal experimentation and with specific resources as to how it can be reduced, refined or replaced. 

genOway offers industry scientists immediate access to EUCOMM conditional KO mouse models.

The booklet is aimed at anyone working with or caring for GA animals, those responsible for recording or maintaining records of GA animals, and/or those involved in the import, export or transport of GA animals. 

This page provides access to searchable, hypertext listings of inbred strains of mice and inbred strains of rats. Both sets of information were provided by Dr. Michael FW Festing (MRC Toxicology Unit) and were converted for Web presentation by the Mouse Genome Informatics Group at The Jackson Laboratory.

In 2006, the Transgenic Training Working Group (TTWG) was formed to identify and provide specific training for carers and users of genetically altered animals.

This gateway provides a place for researchers funded by the NC3Rs to promote the 3Rs impact of their work, and publish rapidly, in an open and transparent manner.

The Sanger Mouse Genetics Programme (Sanger MGP) was initiated in 2006 to advance the functional understanding of protein coding and non-coding RNA genes using a standardised high-throughput phenotypic screen designed to contribute to improved diagnosis and treatment of human disease.

INFRAFRONTIER aims to build a world-class research infrastructure that provides the biomedical research community with the tools needed to unravel the role of gene function in human disease.

General information collated to help with the implementation of approaches to reduce and refine the use of GA mice.