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3Rs

Mandatory Alternatives Petition (US)

The Mandatory Alternatives Petition seeks to change the way drug testing is done in laboratories before drugs are tested on people.

Topic: Replacement

RSPCA Refining Rabbit Welfare

In 2008, the UFAW/RSPCA Rabbit Behaviour and Welfare Group produced a resource that sets out practical guidance on fulfilling the basic needs of the rabbit.

Topic: Refinement

Using 3D Cell Models to Screen Out Ineffective Agents Before Animal Studies

Scientists at the ICR are growing spheres of cancer cells in the laboratory which are designed to mimic the properties of solid tumours.

Topic: Replacement

HemaTIP™ Microsampler

Collecting blood for serology testing from research animals can be a challenging process that leads to increased stress in your animal. Exclusive to Charles River, our HemaTIP™ microsampler simplifies this process by placing the collection media on the tip of an easy-to-hold stylus.

Topic: Refinement

FRAME-Alternatives Lab

The FRAME lab uses cells derived from human tissues to produce biologically relevant in vitro models of human organs, which behave and respond in the way they would in the body.

Topic: Replacement

Humane Endpoints-NC3Rs

There are several stages to consider when planning and carrying out studies involving animals to establish, implement and refine humane endpoints.

Topic: Refinement

Ethical Science Education (Library of Alternatives for Disection)

US-Founded in 1895, the New England Anti-Vivisection Society (NEAVS) is a Boston-based, national animal advocacy organization.

Topic: Replacement

RSPCA Housing and Care Resources

A resource from the research animals department on how housing and care can be refined to reduce suffering and improve welfare of animal species.

Topic: Refinement

Plan to Replace Animal Use Shared at Public Forum

Representatives of federal agencies invited the public to the annual meeting, held at the National Institutes of Health (NIH) in Bethesda, Maryland.

Topic: Replacement

Guidelines for the Care and Use of Animals in Research and Teaching

Norecopa has constructed four databases, which together with all the text on this website can be searched simultaneously using the search field at the top of every page.

Topic: Refinement

Alternatives-NIH-USA-ICCVAM-US

A website with explanations and sources of alternatives.

Topic: Replacement

Welfare assessment-NC3Rs

The term ‘welfare assessment’ applies not only to monitoring animals for signs of pain, suffering and distress associated with procedures, but also to the routine assessment of all animals to check for any health or welfare problems

Topic: Refinement

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