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IMPROVE-ing Animal Welfare in Experimental Stroke Research

Over the last two years, representatives from the UK’s stroke research community have been working, in a collaboration led by the NC3Rs, to improve the welfare and increase the scientific value of rodent models of stroke. The findings from the collaboration - The IMPROVE Guidelines (Ischaemia Models: Procedural Refinements Of in Vivo Experiments)  have been published in the Journal of Cerebral Bloodflow and Metabolism.

Topic: Cardiology

Liverpool University Vetschool Cardiology Department
Topic: Cardiology

Penn Vet School Cardiology Research
Topic: Cardiology

Journal of Veterinary Cardiology
Topic: Cardiology

Animal Research in Pediatric Cardiology and Cardiac Surgery Paper and Pediatric Journal
Topic: Cardiology

JACC: Cardiovascular Interventions Open Access Journal
Topic: Cardiology

General Database Information

The Medical Research Council

The MRC ethics series document ‘Good research practice: principles and guidelines’ sets out the MRC’s expectations for MRC research units and institutes, MRC university units, MRC centres and MRC grant holders in the form of principles, guidelines and standards to foster good research practice in all MRC-funded research.

Topic: Information on drugs and diseases

Medicines Evaluations Board

The Medicines Evaluation Board assesses and monitors the efficacy, risks and quality of human and veterinary medicines, and the safety of novel foods for human consumption.

Topic: Information on drugs and diseases

The Interspecies Database

The Interspecies Database helps researchers to make an optimal choice of species and strain of the animal model, which is essential for efficient extrapolation of animal data to humans or other animals. Thee database has initially been developed by the National Institute for Public Health and the Environment (RIVM) and the Dutch Ministry of Health, Welfare and Sports. It is offered by the 3Rs-Centre ULS in collaboration with the RIVM.

Topic: Information on drugs and diseases

WHO Collaborating Centre for Drug Statistics Methodology
Topic: Information on drugs and diseases

World Health Organisation-Latest News
Topic: Information on drugs and diseases

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