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University Biomedical Services (UBS)

 

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Liverpool University Vetschool Cardiology Department
Topic: Cardiology

Penn Vet School Cardiology Research
Topic: Cardiology

Journal of Veterinary Cardiology
Topic: Cardiology

Animal Research in Pediatric Cardiology and Cardiac Surgery Paper and Pediatric Journal
Topic: Cardiology

JACC: Cardiovascular Interventions Open Access Journal
Topic: Cardiology

IMPROVE-ing Animal Welfare in Experimental Stroke Research

Over the last two years, representatives from the UK’s stroke research community have been working, in a collaboration led by the NC3Rs, to improve the welfare and increase the scientific value of rodent models of stroke. The findings from the collaboration - The IMPROVE Guidelines (Ischaemia Models: Procedural Refinements Of in Vivo Experiments)  have been published in the Journal of Cerebral Bloodflow and Metabolism.

Topic: Cardiology

General Database Information

Fund for the Replacement of Animals in Medical Experiments (FRAME)

FRAME is dedicated to the development of new and valid methods that will replace the need for laboratory animals in medical and scientific research, education, and testing. Where the use of animals is currently necessary, FRAME supports the reduction of numbers involved to an unavoidable minimum and refinement of experimental procedures to minimise any suffering caused. The E-learning resource of FRAME has been set up to provide teachers, school children, students and general supporters with information about the different areas of animal experimentation and with specific resources as to how it can be reduced, refined or replaced. 

Topic: Portals and Websites

3rs-Reduction

3rs-Reduction is a new interactive web-site designed to help scientists to improve the design of their animal experiments. Animal experiments are not always well designed, leading to both ethical concerns and a waste of scientific resources. This is a world-wide problem. Training scientists is difficult as there so are few statisticians with a good understanding of laboratory animal science able to provide such training. This new web-site is designed to help scientists to teach themselves the necessary skills. After an introduction on the ethics of animal experimentation, showing that improvements are needed, it goes on to  cover choice of experimental units, avoiding bias, power and sample size, controlling variability, types of experimental design, factorial experiments, statistical analysis and publication guidelines. Most sections are followed by a "Test yourself" page of true/false questions. The web-site is free. 

Topic: Portals and Websites

Humane Endpoints Website

Humane Endpoints Website is provided by 3Rs-Centre Utrecht Life Sciences, gives insight into the recognition and application of humane endpoints in rodents. The website contributes to refinement, the prevention of unnecessary suffering in laboratory animals, by offering information, videos and photographs of rodent species. In addition, the website provides free training modules (accessible after registration). The site is currently available in EN, NL and FR. DE and ES will follow soon.

Topic: Portals and Websites

InVitro Jobs

The aim of "InVitroJobs" is to enable researchers to access this branch of research more easily. Alongside the job search portal, the site maintains an up-to-date list of research groups active in the development of animal-free techniques. The primary aims of this list are to advertise job vacancies, to provide students with the opportunity to contact these research groups directly to obtain information for thesis assignments and to promote cooperation, networking and the exchange of ideas between researchers. 

Topic: Portals and Websites

NC3Rs: National Centre for Three Rs, UK

A mainly government funded body which provides input to the UK’s Three Rs agenda, carries out research and provides funds for Three R research. 

Topic: Portals and Websites

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